منابع مشابه
Evolution of vitamin B2 biosynthesis: 6,7-dimethyl-8-ribityllumazine synthases of Brucella.
The penultimate step in the biosynthesis of riboflavin (vitamin B2) involves the condensation of 3,4-dihydroxy-2-butanone 4-phosphate with 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione, which is catalyzed by 6,7-dimethyl-8-ribityllumazine synthase (lumazine synthase). Pathogenic Brucella species adapted to an intracellular lifestyle have two genes involved in riboflavin synthesis, ribH1 and...
متن کاملParenchymatous Keratitis Following Riboflavin (Vitamin B2) Deficiency
Riboflavin or vitamin B2 (no. 1), a definite member of the 1 vitamin B complexis a pigment of the flavin type and has the empirical formula C17H20N4O?. It has also been called vitamin G, lactoflavin and ovaflavin. The other vitamin B2 (no. 2)?the P-P factor, nicotinic acid?has the formula C0H4N COOH, and its amide, C6H4N CONH?. Riboflavin has been isolated in pure form from liver, yeast and mil...
متن کاملVitamin B2 (riboflavin) and a mixture of vitamin B2 and C affects MMC efficiency in aerated media under irradiation.
Vitamin B2 (Riboflavin) acts as a strong radiation protecting agent in Escherichia coli bacteria (AB1157) in aerated media. This ability is reinforced by the addition of vitamin C. Under the influence of gamma-radiation, vitamin B2 completely suppresses the cytostatic activity of mitomycin C (MMC). In the presence of both vitamins, B2 and C, MMC is converted from an efficient cytostatic to a ra...
متن کاملEvolution of vitamin B2 biosynthesis: structural and functional similarity between pyrimidine deaminases of eubacterial and plant origin.
The Arabidopsis thaliana open reading frame At4g20960 predicts a protein whose N-terminal part is similar to the eubacterial 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate deaminase domain. A synthetic open reading frame specifying a pseudomature form of the plant enzyme directed the synthesis of a recombinant protein which was purified to apparent homogeneity and was shown by NMR s...
متن کاملSome recently characterized members of the vitamin B2 complex.
Rossiter, R. J. (1940). Rydin, H. (1935). Schlenk, F. and Snell, E. E. (1945). Sealock, R. R., Livermore, A. H. and Evans, C. A. (1943). 65, 935. Silverman, M. and Werkman, C. H. (1939). Silverman, M. and Werkman, C. H. (1941). Sinclair, H. M. (1933). Sober, H. A., Lipton, M. A. and Elvehjem, C. A. (1940). Still, J. (1941). Biochem. J . 35, 380. Straub, F. B. (1939). Biochem. J . 33, 787. Strau...
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ژورنال
عنوان ژورنال: European Journal of Biochemistry
سال: 2002
ISSN: 0014-2956
DOI: 10.1046/j.1432-1033.2002.03239.x